LH, FSH and Testesterone in ESRD

From: http://www.springerlink.com/content/54181u74353284m3/

A prospective analysis of testicular androgenic function in recipients of a renal allograft
Rajiv Yadav1, S. N. Mehta2, A. Kumar3, S. Guleria2, V. Seenu2 and S. C. Tiwari4
(1)
Department of Urology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
(2)
Department of Surgical Disciplines, All India Institute of Medical Sciences, New Delhi, 110029, India
(3)
Department of Reproductive Biology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, India
(4)
Department of Nephrology, All India Institute of Medical Sciences, New Delhi, 110029, India
Received: 3 February 2007 Accepted: 16 August 2007 Published online: 8 April 2008
Abstract Eighteen adult males with end stage renal disease (ESRD) were studied to determine the serum levels of gonadotropins (LH and FSH), prolactin (PRL) and testosterone. All of the patients were studied longitudinally while undergoing maintenance hemodialysis (HD) and six months after renal transplantation. Prior to transplantation, significantly high levels of gonadotropins and PRL were observed. During HD the serum testosterone levels tended to be subnormal in most of the uremic patients and low normal in some of the subjects. Renal transplantation led to a significant improvement (P < 0.05) in serum testosterone. Elevated gonadotropin and PRL levels observed in patients on HD returned to the normal range in most of the patients after successful renal transplantation.
Keywords End stage renal disease - Hemodialysis - Renal transplantation - Prolactin - Testosterone